For a long time I was never sure if Extremis was a canonical story or not. It just seemed so weird, giving Stark actual powers (though nothing compared to what he's got now).

I saw the motion capture comic version of this on Netflix a few months ago. It's a pretty good adaptation!

/ still gnashes his teeth at the "body repair center part of the brain." Yes, Comic Book Science is often full of weird stuff like that, but this struck me as egregiously bad.