I've thought long and hard about what to put into this category. I originally wanted it to be Joker & Penguin, but then I realized that that friendship doesn't really exist anywhere except in my own head. Then I considered Harvey Dent & Bruce Wayne, but to this day, posting about anything Two-Face-related makes me feel like I'm stepping into thehefner's old underwear.
Then, it struck me.
I only began reading The Sandman
last month, and already, I'm amazed by Neil Gaiman's skills as a storyteller. The longer story arcs are, by turns, confusing, rewarding, trippy, heartwarming and heartbreaking, but what I really respect is that Gaiman never lost his skill for the done-in-one. Almost every one of the longer story arcs is punctuated by a little one-shot issue that may or may not tangentially tie into the larger scope of things, and it's in these that I find the comic's most memorable bits.
Case in point: Hob Gadling, the man who might be called the anti-Ra's al-Ghul. A man of little inherent talent, who stumbled onto immortality almost totally by accident, held on to it through sheer optimism, and never rose toward any truly lofty ambitions. He's not a perfect man by any stretch of the imagination, but he never makes any particular pretensions to morality, either.
Oh, and he befriends a god in the process.
(Well, Gaiman insists that the Endless aren't gods, but it's the same principle - all-powerful, supernatural being that tiny mortals can't hope to ever fully comprehend.)
All because he woke up one day and went...( Dream used to wonder what friendship could be... )