The one that ended X's Better Off Dead arc this August, between the book's titular protagonist and the evident major antagonist of the Dark Horse line it's a part of (Project Black Sky, which's basically several superhero books set in a shared universe that's like a less somber Planetary), was well done as a battle between someone with superpowers and someone without.
It'd begun in this August's issue #15, with X's crashing a meeting between the two men whose forces'd been at war with each other across the city of Arcadia: the astrologically fixated mobster Carmine Tango and the very wealthy foreigner Peter Winter. The latter'd just beaten the former, having gotten him to drink poisoned wine and induced his loyal second-in-command to turn traitor, and was about to learn everything he knew about X..
.. when in came the vigilante in question through the window of the restaurant they were in, sword in hand.
(Before I go any further, a heads up: there's some explicit violence under the cut.)( Well, sword in one hand and unfortunate henchman of Winter's in the other.. but that guy didn't even show up on the next page, so.. )