Chameleon's perceived sexuality is pretty interesting to me. IIRC part of the reason they made him and Kraven brothers is because fans noticed connections between the two and drew thier own conclusions. If anything having a crush on Spider-Man (the OTHER guy who beats him up and calls him names) seems like a return to a previous status quo.

Plus this is a character who has been shown to have struggles with his identity since at least the 90s.