While technically not comic book characters, these ladies have left a lasting impact in the generation that grew up with A: TLA. The show was rich universe to play around with in, with actual characters with motivations. These were not cookie cutter ladies, but true individuals with issues and personal drama, and they all in their own special way rose to the meet the challenges presented to them, as heroes or villains.
And they do get great moments in the filler comics between Seasons.
( Once more unto the breach )